Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Detomidine impurity B European Pharmacopoeia (EP) Reference Standard | 83902-12-9 |
Detomidine impurity B European Pharmacopoeia (EP) Reference Standard | Mol Wt: 292.37 | 83902-12-9 |
Selleck Chemical LLC Imatinib Mesylate S1026-1g
Imatinib Mesylate is an orally bioavailability mesylate salt of Imatinib which is a multi-target inhibitor of v-Abl c-Kit and PDGFR with IC50 of 0 6 M 0 1 M and 0 1 M in cell-free or cell-based assays respectively Imatinib Mesylate (STI571) induces autophagy
Medchemexpress LLC N-acetyl mesalazine | 51-59-2 | 99.9% | C9H9NO4 | 5 MG
N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid and serves as a biomarker for evaluating its efficacy. It can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. This compound can be used in the study of diseases such as colitis and colon cancer.
- Primary intestinal metabolite of 5-aminosalicylic acid
- Serves as a biomarker for evaluating efficacy of 5-aminosalicylic acid
- Scavenges free radicals
- Reduces DNA base hydroxylation
- Ameliorates mucosal inflammation
- Can be used in the study of diseases such as colitis and colon cancer
- Inhibits OH radical-stimulated DNA base hydroxylation in calf thymus DNA
Medchemexpress LLC Abemaciclib Impurity 1 | 1231930-33-8 | 99.4% | C11H12BrFN2 | 1 G
Abemaciclib Impurity 1 (6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole) is a drug intermediate for the synthesis of various active compounds. This product is for research use only and has not been fully validated for medical applications.
- Target: Drug intermediate
- Pathway: Others
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- For research use only
Medchemexpress LLC 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole | 1231930-33-8 | MFCD16660227 | C11H12BrFN2 | 500 G
Abemaciclib Impurity 1 (6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole) is a drug intermediate used for the synthesis of various active compounds. It is intended for use as a laboratory chemical and in the manufacture of substances. This product is for research use only and has not been fully validated for medical applications.
- Functions as a drug intermediate
- Appears as a solid
- Molecular weight of 271.13
- Stable under recommended storage conditions
- Store powder at -20°C for up to 3 years or 4°C for up to 2 years
- Store in solvent at -80°C for up to 6 months or -20°C for up to 1 month
Sigma Aldrich Fine Chemicals Biosciences Alitame - Alanine Amide Impurity United States Pharmacopeia (USP) Reference Standard | 80875-07-6 | 25MG
Alitame - Alanine Amide Impurity United States Pharmacopeia (USP) Reference Standard | Mol Wt: 216.34 | 80875-07-6 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Sulbactam sodium European Pharmacopoeia (EP) Reference Standard | 69388-84-7 |
Sulbactam sodium European Pharmacopoeia (EP) Reference Standard | 69388-84-7 |
Sigma Aldrich Fine Chemicals Biosciences Vinpocetine impurity C European Pharmacopoeia (EP) Reference Standard | 70155-05-4 |
Vinpocetine impurity C European Pharmacopoeia (EP) Reference Standard | Mol Wt: 380.48 | 70155-05-4 |
Sigma Aldrich Fine Chemicals Biosciences Nimodipine Related Compound B United States Pharmacopeia (USP) Reference Standard | 70172-96-2 | 50MG
Nimodipine Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 434.44 | 70172-96-2 | 50MG
Medchemexpress LLC Capreomycin (sulfate) | 1405-37-4 | 99.5% | 1 G
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. It exhibits anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting amyloid fibrillation. This product is suitable for studies related to multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease, and Parkinson's disease.
- Inhibits insulin fibril formation in human erythrocytes.
- Protects against amyloid fibril-induced erythrocyte damage and hemolysis.
- Destroys fibrils in erythrocytes in a time-dependent manner.
- Decreases wet lung weight and bacterial burden in the lungs of infected guinea pigs.
- Appearance: solid.
- Color: white to off-white.
- Initial source: microorganisms (Streptomyces capreolus).
- Storage: -20°C, sealed, away from moisture.
- Solubility in H2O: 100 mg/mL (requires ultrasonic).
![Medchemexpress LLC 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)- | 147098-18-8 | 99.9% | 503.52 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386888-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)- | 147098-18-8 | 99.9% | 503.52 | 200 MG
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. It potently blocks hERG current with an IC50 of 195 nM. This compound effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
- Reduces the expression of mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein.
- Effectively lowers low-density lipoprotein (LDL) cholesterol.
- Reduces triglyceride levels.
- Decreases C-reactive protein levels.
Medchemexpress LLC Rosuvastatin | 287714-41-4 | 481.54 | 5MG
Rosuvastatin | 287714-41-4 | 481.54 | 5MG
Medchemexpress LLC Metoprolol succinate | 98418-47-4 | 99.6% | 652.82 | 100 MG
Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. It exhibits anti-inflammatory, antitumor, and anti-angiogenic properties. Metoprolol has also shown cytotoxic effects on U937 and MOLT-4 cells in a dose and time-dependent manner.
- Orally active
- Selective β1-adrenoceptor antagonist
- Anti-inflammation properties
- Antitumor properties
- Anti-angiogenic properties
Medchemexpress LLC Losartan (potassium) | 124750-99-8 | 99.98% | 461.00 | 1 ML
Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM.
- Targets angiotensin receptor
- Used in research for cardiovascular disease, endocrinology, and cancer
- Functions as an antagonist of angiotensin II receptor type 1 (AT1)
Medchemexpress LLC Salmeterol xinafoate | 94749-08-3 | 99.9% | 603.75 | 1 ML
Salmeterol xinafoate is a potent and selective human β2 adrenoceptor agonist. It shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors.
- Potent and selective human β2 adrenoceptor agonist.
- Inhibits human T lymphocyte proliferation.
- Therapeutic effects in mice with chronic obstructive pulmonary disease (COPD).